Looking for Information on CIGX and Anatabloc?
Star Scientific (CIGX) has become one of the most searched for stocks on the internet. Hopefully, some of the people looking for information on Star Scientific and Anatabloc will find their way to Investors Hub and this discussion board. Not only does this board focus our discussions on the investment opportunity that Star Scientific offers, we have numerous individuals (myself included) that actually take Anatabloc and share our experiences.
I have predicted that Star Scientific (CIGX) will be a big winner in 2012. In fact, CIGX has the possibility of being another "It Stock" ala QCOM in 1999. If you have never read this article in Money Magazine, I highly recommend you read it...if only for nostalgia purposes.
http://money.cnn.com/magazines/moneymag/moneymag_archive/2000/03/01/274048/index.htm
Based on the research attached below, I believe CIGX will wind up being the "It Stock" for 2012, and, IMHO, it will be at least a ten bagger in 2012. To do that it has to get >$22 (CIGX closed the last day of 2011 at 2.18).
Why am I so high on Star Scientific? First...here's a little history.
Star Scientific is a small company located outside Richmond, VA that developed and patented a methodology to cure tobacco that virtually eliminates the formation of the primary carcinogen in tobacco (TSNA’s or tobacco specific nitrosamines). Star Scientific patented a process to cure tobacco that controlled the heat, humidity, and the aerobic conditions in the curing barns that significantly reduced the TSNA’s. Those patents were recently validated by the US Patent and Trademark Office and by the Federal courts. Also, new Star patents that reduce TSNA's to below detectable levels (BDL) were recently granted by the USPTO and they are good until 2032. This summer Star Scientific and RJ Reynolds (RAI) will be in court ordered mediation talks (if they don't settle before then). But that is not the interesting part of this story. The interesting part of the story revolves around the health effects of another compound Star found in tobacco called anatabine.
While Star Scientific was working on ways to benefit smokers from their knowledge of tobacco, they started searching for another substance in tobacco that might be used to help smoker's stop smoking (they suspected there was something in addition to nicotine and they were correct). They found another substance in tobacco similar to nicotine called anatabine. Anatabine is a minor alkaloid in tobacco and it is also in foods such as green tomatoes, eggplant, peppers, and cucumbers. In testing, Star discovered that anatabine had some remarkable properties to reduce inflammation.
Star was selling an over the counter product with anatabine called CIGRx about 3 years ago to help smokers stop smoking. That product helped some people with their nicotine addiction, but had no effect on others. However, people taking CIGRx to stop smoking started noticing unforeseen health benefits (especially people with autoimmune diseases).
The company got independent medical experts involved from Johns Hopkins and from the Roskamp Institute in Sarasota, FL (an independent research facility on aging and Alzheimers partially funded by NIH). For several years these experts have been studying the anti-inflammatory response for patients taking Anatabloc (code name RCP-006 at the Roskamp Institute). They have now verified that Anatabine Citrate (the active ingredient in Anatabloc) has some remarkable properties to reduce inflammation. Because it is a nutraceutical, Star Scientific was able to get it to market much faster than a drug because it did not have to go through the FDA drug approval process. They also found a way to synthesize it artificially and make pure Anatabine (and the patent approval notice of allowance was recently granted by the USPTO).
Anatabloc is now available by mail order over the internet at anatabloc.com and it is also available in GNC stores where sales have recently seen a dramatic increase. The product is safe because it is a nutraceutical (found in everyday foods such as tomatoes, eggplants, and peppers at lower concentrations). We can't eat 20-25 pounds of green tomatoes every day, but we can take six tablets (lozenges) of Anatabloc. Attached below is a good background article on inflammation that was in Time Magazine a few years ago. In a nutshell, it says that inflammation may be the root cause of a variety of illnesses (including auto immune diseases, heart disease, Parkinsons, Alzheimers, MS, and many cancers).
http://www.time.com/time/magazine/article/0,9171,993419,00.html
Many people have now been taking Anatabloc since late last summer and have experienced relief from a variety of afflictions related to autoimmune diseases and other serious conditions. Here is a recent news piece from a CBS affiliate station in Michigan (WNEM) where a reporter interviewed a woman participating in one of the Anatabloc human trials. They also interviewed the local doctor (Dr. Dale Wilson) who was coordinating the trial. Watch the video linked below (and pay close attention to what Dr. Wilson says near the end about participants in the trial showing a "marked response"). These results should be released in the next month or two.
http://www.youtube.com/watch?v=StVre96Vzr8
Here is another video testimonial from world reknown Tennis academy director, Nick Bollitieri, along with former world ranked tennis players Jimmy Arias and Aaron Krickstein
http://www.youtube.com/watch?v=sonBc4SbWbg
Testimonials on the internet started appearing about 2 years ago, after people started using CIGRx. The anti-inflammatory properties of anatabine was helping a variety of people with the symptoms of autoimmune diseases. I saw some of these testimonials myself, yet I was extremely skeptical of all this until I learned that physicians from Johns Hopkins and the Roskamp Institute had verified these anti-inflammatory properties. Dr. Paul Ladenson (Director of Endocrinology and Metabolism at Johns Hopkins), Dr. Patruzo Caturegli of Johns Hopkins, and Dr. Michael Mullan (Director of the Roskamp Institute in Sarasota, FL) had tested Anatabloc and were fully convinced about the efficacy for reducing inflammation (they are now giving seminars to other physicians).
My Experience with Anatabloc is documented here.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=75242570
Anatabine Test Results
Anatabine has passed numerous studies in mammals and is now being used in several clinical trials with humans (CRP Trial, Thyroiditis trial, Alzheimer's trial, etc.). Attached below are links to Anatabloc's (code name RCP-006) anti-inflammatory test results released from the The Roskamp Institute. They reveal that Anatabine (Anatabloc) reduces inflammation much better than Aspirin, Advil or Celebrex (by a factor of four or more). Other test results on mice and rats have shown Anatabine to be non-toxic even at extremely high doses (100 times the equivalent recommended dose for humans). The first product that Star Scientific sold with anatabine was CIGRx to help smokers stop smoking. CIGRx only had .3 mg of Anatabine or about 1/3rd the anatabine content that is in their new product (Anatabloc has 1 mg). Over 300,000 people have now taken CIGRx and/or Anatabloc with no reported drug interactions, so anatabine is apparently safe. Below are the results published by the Roskamp Insitute on the ability of Anatabine to reduce inflammation.
http://www.rfdn.org/inflammaging.html
http://www.rfdn.org/inflammaging2.html
http://www.rfdn.org/inflammaging3.html
http://www.mullanalzheimer.com/livesite/
IMHO, Anatabloc will have significant benefits for numerous auto-immune related diseases associated with inflammation (including Rheumatoid Arthritis, Asthma, Crohn's Disease, MS, etc.). I have numerous friends that have taken Anatabloc with great results. Recent testimonials on the internet also support the fact that it has greatly benefitted people with other conditions associated with inflammation associated with NF-kB (including cancers, Alzheimers, Parkinsons etc.). There have been dozens of anecdotal stories of miraculous cures posted on the internet. For example...here is one posted by someone who was apparently cured of bladder cancer.
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=69786883
There are dozens of testmonials like this on the internet, from Plantar Fasciatis to Periodontitis. The world is waiting for Star to release peer reviewed medical journal articles and studies of on-going human trials on Anatabloc and this is apparently imminent based based on public comments. The first medical journal article (on In-vivo and In-Vitro effects of Anatabine for Alzhiemers) was released late last year, but a lot more should be coming out in 2012, starting at any time.
Patrick Cox (a technology stock analyst who has toured the Roskamp Institute and talked to physicians at Johns Hopkins involved with Anatabloc studies) wrote an article about Anatabloc that explains the huge upside of a nutraceutical that can stop NF-kB inflammation.
http://xa.yimg.com/kq/groups/14511094/1089346374/name/^2011-03-18+Anatabine+Issue_noPortfolio.pdf
Here are a few of the testimonials that have been posted on the Investor Village CIGX board....
http://www.investorvillage.com/smbd.asp?mb=2013&mn=1214&pt=msg&mid=11240113
http://www.investorvillage.com/smbd.asp?mb=2013&mn=1202&pt=msg&mid=11237539
http://www.investorvillage.com/smbd.asp?mb=2013&mn=1201&pt=msg&mid=11236384
http://www.investorvillage.com/smbd.asp?mb=2013&mn=527&pt=msg&mid=11070806
http://www.investorvillage.com/smbd.asp?mb=2013&mn=810&pt=msg&mid=11154476
http://www.investorvillage.com/smbd.asp?mb=2013&mn=498&pt=msg&mid=11045528
http://www.investorvillage.com/smbd.asp?mb=2013&mn=1024&pt=msg&mid=11206013
http://www.investorvillage.com/smbd.asp?mb=2013&mn=861&pt=msg&mid=11176972
http://www.investorvillage.com/smbd.asp?mb=2013&mn=848&pt=msg&mid=11174981
http://www.investorvillage.com/smbd.asp?mb=2013&mn=842&pt=msg&mid=11174283
http://www.investorvillage.com/smbd.asp?mb=2013&mn=839&pt=msg&mid=11174087
http://www.investorvillage.com/smbd.asp?mb=2013&mn=1040&pt=msg&mid=11209344
http://www.investorvillage.com/smbd.asp?mb=2013&mn=841&pt=msg&mid=11174268
http://www.investorvillage.com/smbd.asp?mb=2013&mn=865&pt=msg&mid=11177489
I personally know about 60 people who are taking Anatabloc, and almost all have reported positive benefits (some have reported numerous positive benefits). I'm sure it won't help everybody, but it seems to help most people. These positive reports are not a simple placebo effect, because I know of several people (myself included), who have their symptoms return when not taking Anatabloc for several days.
At present, all we know is that Anatabloc does assist in preventing the NF-kB inflammation process from going haywire in the body. So, in theory, any human disease condition caused by excess NF-kB inflammation could be helped by Anatabloc.
In case you are interested, here are a few human diseases where NF-kB inflammation plays a role
http://www.bu.edu/nf-kb/physiological-mediators/diseases/
excerpts...
Diseases
NF-kB DISEASES
On this page are listed several diseases in which activation of NF-kB has been implicated. For general reviews on the role of NF-kB in disease, see Aradhya & Nelson (2001), Kumar et al (2004), Yamamoto & Gaynor (2002) or Baldwin (2001). For specific diseases see the listed references, which can be found either on this site (under References) or at PubMed (through the linked references).
Table 1: General Diseases
Disease Review/Paper
Ageing Chung et al, 2002; Adler 2007; Csizar 2008
Allergies Cousins et al, 2008
Headaches Reuter et al, 2003
Pain Tegeder 2004; Niederberger 2008
Complex Regional Pain Syndrome Hettne et al, 2007
Cardiac Hypertrophy Purcell 2003; Freund et al, 2005; Sen 2005
Muscular Dystrophy (type 2A) Baghdiguian et al, 1999
Muscle wasting Hasselgren, 2007
Catabolic disorders Holmes-McNary, 2002
Diabetes mellitus, Type 1 Ho & Bray, 1999; Eldor 2006
Diabetes mellitus, Type 2 Yuan et al, 2001; Lehrke et al, 2004
Obesity Gil et al, 2007
Fetal Growth Retardation Mammon et al, 2005 Hypercholesterolemia Wilson et al, 2000
Atherosclerosis Ross et al, 2001 ; Li & Gao, 2005
Heart Disease Valen et al, 2001
Chronic Heart Failure Frantz et al, 2003; Gong et al, 2007
Ischemia/reperfusion Toledo-Pereyra et al, 2004; Nichols, 2004
Stroke Herrmann et al, 2005
Cerebral aneurysm Aoki et al, 2007; 2009
Angina Pectoris Ritchie, 1998
Pulmonary Disease Christman et al, 2000
Cystic Fibrosis Pollard 2005; Carrabino 2006; Rottner 2007
Acid-induced Lung Injury Madjdpour et al, 2003
Pulmonary hypertension Sawada et al, 2007
Chronic Obstructive Pulmonary
Disease (COPD) Barnes, 2002 ; Rahman & Kilty, 2006
Hyaline Membrane Disease Cheah et al, 2005
Kidney Disease Guijarro 2001; Camici, 2006; Guzik 2007
Glomerular Disease Zheng et al, 2005
Alcoholic Liver Disease Zima & Kalousova, 2005
Leptospirosis renal disease Yang et al, 2001
Gut Diseases Neurath et al, 1998
Peritoneal endometriosis Gonzalez-Ramos et al, 2007
Skin Diseaes Bell et al, 2003
Nasal sinusitis Xu et al, 2006
Anhidrotic Ecodermal Dysplasia-ID Puel et al, 2005
Behcet’s Disease Todaro et al, 2005
Incontinentia pigmenti Courtois & Israel, 2000
Tuberculosis Zea et al, 2006
Asthma Pahl & Szelenyi, 2002
Arthritis Roshak et al, 2002 ; Aud & Peng, 2006
Crohn’s Disease Pena & Penate, 2002
Colitis (rat) Chen et al, 2005
Ocular Allergy Bielory et al, 2002
Glaucoma Zhou et al, 2005
Appendicitis Pennington et al, 2000
Paget’s Disease Lin et al, 2007
Pancreatitis Weber & Adler, 2001 ; Gray et al, 2006
Periodonitis Nichols et al, 2001; Ambili et al, 2005
Endometriosis Guo, 2006; Celik et al, 2008
Inflammatory Bowel Disease Dijkstra et al, 2002; Atreya et al, 2008
Inflammatory Lung Disease Park & Christman, 2006
Sepsis Wratten et al, 2001; Abraham, 2003
Silica-induced Chen & Shi, 2002
Sleep apnoea Lavie, 2003
AIDS (HIV-1) Hiscott et al., 2001
Autoimmunity Bacher & Schmitz, 2004
Antiphospholipid Syndrome Lopez-Pedrera et al, 2005
Lupus Okamoto, 2006; Oikonomidou 2007
Lupus nephritis Zheng et al, 2006,
Chronic Disease Syndrome Maes et al, 2007
Familial Mediterranean Fever Onen, 2005
Hereditary Periodic Fever Syndrome Jeru et al, 2008
Psychosocial stress diseases Bierhaus et al, 2004
NeuropathologicalDiseases Pizzi & Spano, 2006
Familial amyloidotic polyneuropathy Mazzeo et al, 2004
Traumatic brain injury Hang et al, 2005
Spinal cord injury Brambilla et al, 2005
Parkinson Disease Soos et al, 2004, Mogi et al, 2006
Multiple Sclerosis Satoh et al, 2007
Rheumatic Disease Okamoto, 2006; Greetham et al, 2007
Alzheimers Disease Collister & Albensi, 2005
Amyotropic lateral sclerosis Xu et al, 2006
Huntington’s Disease Khoshnan et al, 2004
Retinal Disease Kitaoka et al, 2004
Cataracts Yang et al, 2006
Hearing loss Merchant et al, 2005; Lang et al, 2006
Cancer Gilmore 2002; Lee et al, 2007 (see Table 2, below)
______________________________________________________________________
.
Table 2: Constitutive activation of NF-kB in human cancer cells
Cancer type Reference
A: Primary tumors and tumor cell lines
Solid tumors (generally) Pacifico & Leonardi, 2006
Breast Nakshatri 1997; Sovak1997; Ahmed et al, 2006
Cervix Nair 2003; Kumar et al, 2005; Ramdass et al, 2006
Ovary Dejardin et al, 1999; Huang et al, 2000
Vulva Seppanen & Vihko, 2000
Prostate Huang 2001; Fradet 2004; Lessard 2006; Paule 2007
Kidney Oya et al, 2001, 2003
Bladder Horiguchi 2003; Kadhim 2006; Levidou 2008
Lung Zhang et al, 2007; Motadi 2007; Stathopoulos 2008
Mesothelioma Bertino 2007; Carbone & Bedrossian, 2006
Non small-cell lung Zhang et al, 2006; Tew et al, 2007; Jin et al, 2008
Liver Arsura & Cavin, 2005; Qiao et al, 2006; Seki 2007
Pancreas Jackson 2006; Sarkar 2006; Holcomb 2008
Stomach Sasaki et al, 2001; Wu et al, 2007
Colon Lind et al, 2001; Schottelius 2006; Aranha et al, 2007
Thyroid Visconti 1997; Pacifico 2004; Gombos et al, 2007
Parathyroid Corbetta et al, 2004
Melanoma Amiri 2005; Ueda 2006; Van den Oord 2007
Squamous cell carcinoma Loercher 2004; Kobielak & Fuchs, 2006
Head and neck Ondrey 1999; Chung 2006; Allen 2007
Endometrial (Uteris) Pallares 2004; Domenyuk et al, 2007
Cylindromatosis Kovalenko 2003; Trompouki et al, 2003
Hilar Cholangiocarcinoma Chen et al, 2005
Oral carcinoma Bindhu 2006; Mishra 2006; Sawhney 2007
Astrocytoma/glioblastoma Hayahsi 2001; Garkavtsev 2004
Neuroblastoma Bian 2002; Brown 2007; Widera 2007
Glioblastoma Raychaudhuri et al, 2007; Smith 2007
Hodgkin’s lymphoma Bargou et al, 1996, 1997; Staudt, 2000
Acute lymphoblastic leukemia Kordes et al, 2000; Munzert 2004
Acute myelogenous leukemia Guzman et al, 2001
Acute T-cell leukemia (+/-HTLV-1) Arima & Tei, 2001; Horie 2006
Acute Non-lymphocytic leukemia Lei & Zhao, 2007
Chronic lymphocytic leukemia Furman et al, 2000 ;
Burkitts Lymphoma (EBV) Knecht et al, 2001
Mantle cell lymphoma Martinez et al, 2003
Myelodysplastic syndrome Fabre et al, 2007
Multiple myeloma Berenson et al, 2001; Gilmore, 2007
Diffuse large B-cell lymphoma Davis et al, 2001; Shaffer et al, 2002
MALT lymphoma Sagaert al, 2007; Inagaki, 2007; Du, 2007
Waldenstrom macroglobulinemia Leleu et al, 2008
